Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27562179 | 0.87 | USP2 (0.51) | L3MBTL1MAPTNPSR1LMNAUSP2 | |
| SCHEMBL28233130 | 0.86 | L3MBTL1 (0.54) | L3MBTL1MAPTNPSR1GLAGAA | |
| SCHEMBL20072234 | 0.83 | MTNR1A (0.59) | — | |
| SCHEMBL27993616 | 0.83 | PTGS2 (0.51) | LMNAHSD17B10ALDH1A1KDM4ETHRB | |
| SCHEMBL13034142 | 0.83 | L3MBTL1 (0.54) | L3MBTL1MAPTNPSR1GLAGAA | |
| SCHEMBL17459123 | 0.83 | L3MBTL1 (0.64) | L3MBTL1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL28241610 | 0.82 | THRB (0.54) | L3MBTL1MAPTNPSR1GLAGAA | |
| SCHEMBL27855924 | 0.81 | PTGS2 (0.45) | L3MBTL1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11341859 | 0.80 | L3MBTL1 (0.54) | L3MBTL1MAPTNPSR1GLAGAA | |
| SCHEMBL16673226 | 0.77 | CYP4F2 (0.67) | L3MBTL1MAPTNPSR1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761809-A | Method for synthesizing 2-bromo-2- (2-fluoro-3-methoxyphenyl) ethyl acetate by catalytic reduction of palladium on carbon | 安徽华胜医药科技有限公司 | 2019-05-17 | — | — | CN | disclosed |
| CN-109734590-A | Method for synthesizing 2-bromo-2- (2-fluoro-3-methoxyphenyl) ethyl acetate by carbon dioxide method | 安徽华胜医药科技有限公司 | 2019-05-10 | — | — | CN | disclosed |