Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.75 |
| ▸ | CA9 | Q16790 | 10/20 | 0.75 |
| ▸ | CA12 | O43570 | 9/20 | 0.75 |
| ▸ | CA1 | P00915 | 9/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724544 | 0.86 | PTGS2 (0.73) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL3384413 | 0.83 | CA2 (0.53) | CA2CA9CA12CA1TAAR1 | |
| SCHEMBL307761 | 0.83 | ALOX5 (0.53) | CA2CA9CA12CA1TAAR1 | |
| SCHEMBL6723983 | 0.82 | CA2 (0.57) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL6726266 | 0.82 | PTGS2 (0.74) | CA2CA1PTGS2PTGS1 | |
| SCHEMBL5011765 | 0.82 | CA2 (0.67) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL6848937 | 0.81 | CA2 (0.68) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL28371316 | 0.81 | CA2 (1.00) | CA2CA9CA1CA13 | |
| SCHEMBL6475078 | 0.80 | CA2 (0.86) | CA2CA9CA12CA1PTGS2 | |
| SCHEMBL16394285 | 0.79 | TAAR1 (0.71) | TAAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715629-A | AZA-INDAZOLE COMPOUNDS FOR USE IN TENDON AND/OR LIGAMENT INJURIES | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |