Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13988943 | 1.00 | CYP19A1 (0.49) | CYP19A1MEN1KMT2AHTTGLA | |
| SCHEMBL2829919 | 1.00 | CYP19A1 (0.49) | CYP19A1MEN1KMT2AHTTGLA | |
| SCHEMBL2537000 | 0.85 | ERN1 (0.53) | CYP19A1MEN1KMT2AHTTGLA | |
| SCHEMBL28585971 | 0.84 | CYP19A1 (0.50) | CYP19A1MEN1KMT2AHTTGLA | |
| SCHEMBL16958259 | 0.84 | CYP19A1 (0.50) | CYP19A1MEN1KMT2AHTTGLA | |
| SCHEMBL10017635 | 0.84 | CYP19A1 (0.50) | CYP19A1MEN1KMT2AHTTGLA | |
| SCHEMBL5740241 | 0.83 | NFE2L2 (0.52) | CYP19A1MEN1KMT2AHTTGLA | |
| SCHEMBL5740242 | 0.83 | NFE2L2 (0.52) | CYP19A1MEN1KMT2AHTTGLA | |
| SCHEMBL29860729 | 0.81 | CYP19A1 (0.48) | CYP19A1MEN1KMT2AHTTGLA | |
| SCHEMBL16307958 | 0.81 | CYP19A1 (0.48) | CYP19A1MEN1KMT2AHTTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448404-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2025-10-21 | — | — | US | disclosed |
| EP-3356379-B2 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS SA (PL) | 2025-09-03 | — | — | EP | disclosed |
| US-20250066402-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS SA (PL) | 2025-02-27 | — | — | US | disclosed |
| US-12173015-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2024-12-24 | — | — | US | disclosed |
| US-11976085-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | Aperion Synthesis S.A. (PL) | 2024-05-07 | — | — | US | disclosed |
| US-20240076308-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS SA (PL) | 2024-03-07 | — | — | US | disclosed |
| US-20220073549-A1 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | APEIRON SYNTHESIS SA (PL) | 2022-03-10 | — | — | US | disclosed |
| US-11192911-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2021-12-07 | — | — | US | disclosed |
| CN-108137631-B | Process for preparing ruthenium complexes and intermediates thereof and their use in olefin metathesis | 阿派朗合成公司 | 2021-04-16 | — | — | CN | disclosed |
| EP-3356379-B1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS SA (PL) | 2021-03-10 | — | — | EP | disclosed |
| US-20180298046-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | APEIRON SYNTHESIS S.A. (PL) | 2018-10-18 | — | — | US | disclosed |
| EP-3356379-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | Apeiron Synthesis S.A. (PL) | 2018-08-08 | — | — | EP | disclosed |
| EP-1948671-B1 | PREPARATION OF CATALYSTS | BOEHRINGER INGELHEIM INT (DE) | 2010-09-29 | — | — | EP | disclosed |
| US-20080319199-A1 | Preparation of Catalysts | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-12-25 | — | — | US | disclosed |
| EP-1948671-A1 | PREPARATION OF CATALYSTS | Boehringer Ingelheim International GmbH (DE) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007054483-A1 | PREPARATION OF CATALYSTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12448404-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | CYP2E1, CYP1A1, REV1 | CYP19A1 81/4885MEN1 1376/4885KMT2A 4571/4885 |
| US-20220073549-A1 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | POR, CYP1B1, CYP4F11 | CYP19A1 25/4885MEN1 834/4885KMT2A 4482/4885 |
| US-11976085-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | POR, CYP1B1, CYP4F11 | CYP19A1 25/4885MEN1 834/4885KMT2A 4482/4885 |
| US-11192911-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | POR, CYP1B1, CYP4F11 | CYP19A1 25/4885MEN1 834/4885KMT2A 4482/4885 |
| US-20180298046-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | POR, CYP1B1, CYP4F11 | CYP19A1 25/4885MEN1 834/4885KMT2A 4482/4885 |
| US-12173015-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | POR, CYP1B1, CYP4F11 | CYP19A1 25/4885MEN1 834/4885KMT2A 4482/4885 |
| US-20080319199-A1 | Preparation of Catalysts | MARS2, DNMT3L, MSL1 | CYP19A1 1664/4885MEN1 8/4885KMT2A 689/4885 |
| US-20250066402-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | CYP2E1, CYP1A1, REV1 | CYP19A1 81/4885MEN1 1376/4885KMT2A 4571/4885 |
| US-20240076308-A1 | PROCESS FOR PRODUCING RUTHENIUM COMPLEXES AND INTERMEDIATES THEREOF AND THEIR USE IN OLEFIN METATHESIS | POR, CYP1B1, CYP4F11 | CYP19A1 25/4885MEN1 834/4885KMT2A 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.