Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GPR3 | P46089 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3067398 | 0.87 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPTGPR3HSD17B10 | |
| SCHEMBL28279288 | 0.83 | MAP2K3 (0.53) | ALDH1A1SMN1; SMN2MAPTGPR3HSD17B10 | |
| SCHEMBL8573192 | 0.83 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2MAPTGPR3HSD17B10 | |
| SCHEMBL28342069 | 0.79 | KDM4E (0.54) | ALDH1A1SMN1; SMN2MAPTGPR3HSD17B10 | |
| SCHEMBL15253806 | 0.78 | ABCG2 (0.57) | ALDH1A1MAPTCYP3A4HIF1AKMT2A | |
| SCHEMBL28592739 | 0.75 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTGPR3DYRK1A | |
| SCHEMBL4121482 | 0.75 | POLB (0.56) | ALDH1A1SMN1; SMN2MAPTCYP1A2CYP3A4 | |
| SCHEMBL29289272 | 0.74 | HSD17B10 (0.45) | ALDH1A1SMN1; SMN2MAPTGPR3HSD17B10 | |
| SCHEMBL9596955 | 0.74 | GPR3 (0.44) | ALDH1A1SMN1; SMN2MAPTGPR3HSD17B10 | |
| SCHEMBL27550242 | 0.73 | PDE10A (0.55) | ALDH1A1SMN1; SMN2MAPTHSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761902-A | 6- phenanthridines ketone derivatives and its preparation method and application | 四川大学 | 2019-05-17 | — | — | CN | claimed |
| CN-109761902-A | 6- phenanthridines ketone derivatives and its preparation method and application | 四川大学 | 2019-05-17 | — | — | CN | disclosed |
| CN-109761902-A | 6- phenanthridines ketone derivatives and its preparation method and application | 四川大学 | 2019-05-17 | — | — | CN | disclosed |
| CN-109761902-A | 6- phenanthridines ketone derivatives and its preparation method and application | 四川大学 | 2019-05-17 | — | — | CN | disclosed |