Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208121 | 0.77 | HSD17B10 (0.42) | VCAM1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1898245 | 0.76 | GRIN2D (0.39) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL27684781 | 0.73 | ALDH1A1 (0.36) | VCAM1MAPTALOX15HPGDTDP1 | |
| SCHEMBL9653201 | 0.73 | ALDH1A1 (0.36) | CYP1A2TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1895507 | 0.72 | ALDH1A1 (0.40) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL6282528 | 0.71 | TSHR (0.42) | VCAM1ALOX15HPGDTDP1ALDH1A1 | |
| SCHEMBL11329936 | 0.71 | VCAM1 (0.62) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL28774035 | 0.69 | ALDH1A1 (0.36) | VCAM1MAPTALOX15HPGDTDP1 | |
| SCHEMBL1343713 | 0.69 | VCAM1 (0.61) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL1624405 | 0.69 | VCAM1 (0.56) | VCAM1MAPTGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622580-B | Benzimidazole as prolyl hydroxylase inhibitors | 詹森药业有限公司 | 2019-06-21 | — | — | CN | disclosed |