Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208121 | 0.83 | HSD17B10 (0.42) | TSHRMAPK1VCAM1ALDH1A1CYP3A4 | |
| SCHEMBL909526 | 0.82 | TSHR (0.44) | TSHRMAPK1VCAM1ALDH1A1CYP3A4 | |
| SCHEMBL2886629 | 0.81 | CYP3A4 (0.39) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6255476 | 0.78 | ALDH1A1 (0.49) | TSHRMAPK1VCAM1ALDH1A1CYP3A4 | |
| SCHEMBL9848798 | 0.78 | TSHR (0.41) | TSHRMAPK1VCAM1ALDH1A1CYP3A4 | |
| SCHEMBL28774035 | 0.78 | ALDH1A1 (0.36) | TSHRMAPK1VCAM1ALDH1A1CYP3A4 | |
| SCHEMBL1891926 | 0.76 | TSHR (0.44) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL3036984 | 0.76 | GPR35 (0.46) | TSHRMAPK1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL1822058 | 0.76 | ALDH1A1 (0.46) | TSHRMAPK1VCAM1ALDH1A1CYP3A4 | |
| SCHEMBL9653201 | 0.74 | ALDH1A1 (0.36) | TSHRMAPK1ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723586-A | ISOINDOLE OR BENZOISOTHIAZOLE DYES; WASH- AND COLORFASTNESS; DIAZOTIZATION | CLARIANT FINANCE (BVI) LIMITED (VG) | 1998-03-03 | — | — | US | claimed |
| US-5633355-A | DISPERSE DYES | SANDOZ LTD. (CH) | 1997-05-27 | — | — | US | claimed |
| US-5420254-A | Monoazo dyes for textiles such as cellulose or polyesters | SANDOZ LTD. (CH) | 1995-05-30 | — | — | US | claimed |
| US-6927193-B2 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2005-08-09 | — | — | US | disclosed |
| US-6613718-B2 | 2,3-Dihydro-2-thioxo-pyrimidinone derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-09-02 | — | — | US | disclosed |
| US-6479435-B1 | OR DIARYL SULFIDES, 1-(4-CHLORO-2-FLUORO-5-(2-PYRIMIDYLOXY)PHENYL)-4-DIFLUOROMETHY L-3-METHYL-1,4-DIHYDRO-1,2,4-TRIAZOLIN-5-ONE FOR EXAMPLE | ISK AMERICAS INCORPORATED | 2002-11-12 | — | — | US | disclosed |
| US-6333296-B1 | FOR CONTRILLING WEEDS | ISK AMERICAS INCORPORATED | 2001-12-25 | — | — | US | disclosed |
| US-6303543-B1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-10-16 | — | — | US | disclosed |
| US-6121201-A | HETEROARYL SUBSTITUTED HALO-PYRAZOLE SUBSTITUTED DIARYL ETHERS OR THIOETHERS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| US-5723586-A | ISOINDOLE OR BENZOISOTHIAZOLE DYES; WASH- AND COLORFASTNESS; DIAZOTIZATION | CLARIANT FINANCE (BVI) LIMITED (VG) | 1998-03-03 | — | — | US | disclosed |
| US-5633355-A | DISPERSE DYES | SANDOZ LTD. (CH) | 1997-05-27 | — | — | US | disclosed |
| US-5420254-A | Monoazo dyes for textiles such as cellulose or polyesters | SANDOZ LTD. (CH) | 1995-05-30 | — | — | US | disclosed |