Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456947 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2208121 | 0.82 | HSD17B10 (0.42) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1891926 | 0.78 | TSHR (0.44) | ALDH1A1TSHRTDP1HSD17B10CYP3A4 | |
| SCHEMBL27684781 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1HSD17B10MAPK1 | |
| SCHEMBL9653355 | 0.77 | MAPT (0.40) | ALDH1A1TDP1HSD17B10MAPK1MEN1 | |
| SCHEMBL9653192 | 0.75 | VCAM1 (0.33) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6282528 | 0.74 | TSHR (0.42) | ALDH1A1TSHRTDP1MAPK1CYP3A4 | |
| SCHEMBL28774035 | 0.73 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1HSD17B10MAPK1 | |
| SCHEMBL1898245 | 0.73 | GRIN2D (0.39) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28299458 | 0.73 | VCAM1 (0.47) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213892-B1 | HERBICIDALLY ACTIVE ENOLS | ROHM AND HAAS COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4781750-A | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0213892-A2 | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |