Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28147852 | 0.83 | ALDH1A1 (0.57) | HTR7MAPTSMN1; SMN2MEN1MAPK1 | |
| SCHEMBL28300954 | 0.81 | SMN1; SMN2 (0.50) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28299743 | 0.78 | RAB9A (0.53) | HTR1AHTR7MAPTNPC1RAB9A | |
| SCHEMBL28299729 | 0.77 | NPC1 (0.46) | HTR1AHTR7MAPTNPC1RAB9A | |
| SCHEMBL27932826 | 0.76 | KDM4E (0.51) | HTR1AHTR7MAPTTDP1MEN1 | |
| SCHEMBL28301021 | 0.76 | CA1 (0.55) | RAB9ARPA1 | |
| SCHEMBL28299578 | 0.75 | NPBWR1 (0.51) | HTR1AHTR7MAPTNPC1RAB9A | |
| SCHEMBL28300981 | 0.75 | CCKAR (0.45) | RAB9ARPA1 | |
| SCHEMBL28301083 | 0.75 | CA1 (0.46) | HTR1AHTR7MAPTNPC1RAB9A | |
| SCHEMBL11819228 | 0.73 | ABL1 (0.73) | HTR1AHTR7MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890822-A | INHIBITORS OF CELLULAR METABOLIC PROCESSES | 安吉奥斯医药品有限公司 | 2019-06-14 | — | — | CN | disclosed |