Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300902 | 0.83 | THRB (0.43) | KDM4EMAPTBRD4ALDH1A1HPGD | |
| SCHEMBL4049129 | 0.80 | TP53 (0.42) | GRM5KDM4EMAPTBRD4ALDH1A1 | |
| SCHEMBL28142358 | 0.73 | CHKA (0.39) | EPHB4KDM4EMAPTABCB1ABCG2 | |
| SCHEMBL28298219 | 0.70 | GSK3A (0.36) | GRM5KDM4EMAPTABCB1ABCG2 | |
| SCHEMBL28298212 | 0.70 | MAPT (0.40) | MAPTALDH1A1HSD17B10 | |
| SCHEMBL27796461 | 0.69 | CSNK2A1 (0.47) | MAPTRAB9APIK3CA | |
| SCHEMBL28298230 | 0.66 | KDM4E (0.51) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL28299575 | 0.65 | PIK3CD (0.46) | EPHB4KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28298209 | 0.64 | PIK3CD (0.48) | KDM4EALDH1A1HPGDPIK3CA | |
| SCHEMBL28299583 | 0.64 | KDM4E (0.55) | KDM4EMAPTALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |