SCHEMBL28299650

SCHEMBL28299650

CCC(c1ccccc1)C1CCCN1C=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP1A2 P05177 1/20 0.39
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
HTT P42858 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4162426 0.80 CHRNB4 (0.40) CYP2D6HTT
SCHEMBL28299649 0.77 CYP3A4 (0.44) CYP3A4CYP2D6CYP1A2HTTLMNA
SCHEMBL24666961 0.72 ALDH1A1 (0.39) CYP3A4CYP2D6CYP1A2
SCHEMBL5593714 0.69 ALDH1A1 (0.57) LMNA
SCHEMBL29182250 0.68 ALDH1A1 (0.56) LMNA
SCHEMBL26629764 0.68 PKM (0.55) CYP2D6CYP1A2LMNA
SCHEMBL27391812 0.68 PKM (0.59) CYP3A4LMNA
SCHEMBL22476487 0.67 PREP (0.37) CYP2D6MTNR1B
SCHEMBL4158230 0.67 AR (0.33)
SCHEMBL18132900 0.67 CYP17A1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105636947-B N- heteroaryl (thio) carbonyl -2- (Benzocycloalkene -1- base) cyclammonium and its purposes as fungicide 拜耳作物科学股份公司 2019-05-07 CN disclosed