Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 5/20 | 0.46 |
| ▸ | SHMT1 | P34896 | 3/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619008 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8847516 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL21560170 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL6229232 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL26319542 | 0.82 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL1422234 | 0.81 | LMNA (0.74) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL4727339 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL26319547 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL20241573 | 0.80 | SHMT1 (0.58) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL8847610 | 0.78 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867666-B | Aromatic acetamide compound containing isothiazole ring and application thereof | 沈阳中化农药化工研发有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-109867666-A | A kind of fragrant acetamides of the ring containing isothiazole and application thereof | 沈阳中化农药化工研发有限公司 | 2019-06-11 | — | — | CN | disclosed |