Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 5/20 | 0.43 |
| ▸ | SHMT1 | P34896 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299739 | 0.87 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL9832171 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL4727339 | 0.80 | ALDH1A1 (0.46) | KDM4EALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL28008732 | 0.80 | ALDH1A1 (0.68) | KDM4EALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL28009248 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL28617272 | 0.73 | LMNA (0.48) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL28873481 | 0.72 | HSD17B10 (0.39) | KDM4EHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL5539775 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL2545992 | 0.72 | ACHE (0.61) | KDM4EALDH1A1TDP1PTGER1 | |
| SCHEMBL26319542 | 0.72 | ALDH1A1 (0.65) | KDM4EALDH1A1TDP1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867666-B | Aromatic acetamide compound containing isothiazole ring and application thereof | 沈阳中化农药化工研发有限公司 | 2021-09-07 | — | — | CN | disclosed |