Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | AOC2 | O75106 | 3/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP7 | P09237 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP14 | P50281 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21929283 | 0.81 | TDP1 (0.50) | MAOAMAOBAOC2CRBNGLP1R | |
| SCHEMBL1782820 | 0.79 | CRBN (0.55) | CRBNALDH1A1GAA | |
| SCHEMBL4595077 | 0.75 | CRBN (0.55) | MAOAMAOBAOC2CRBNMMP2 | |
| SCHEMBL2536571 | 0.75 | MAOA (0.40) | MAOAMAOBAOC2CRBNGLP1R | |
| SCHEMBL2413925 | 0.75 | PLCG1 (0.59) | MAOAMAOBAOC2MMP2MMP9 | |
| SCHEMBL28197182 | 0.74 | CA12 (0.50) | MAOAMAOBAOC2CRBNGLP1R | |
| SCHEMBL11951548 | 0.74 | GLP1R (0.49) | GLP1RMMP2MMP9MMP14CNR2 | |
| SCHEMBL28229855 | 0.74 | ALDH1A1 (0.56) | CRBNMMP2MMP7MMP9MMP14 | |
| SCHEMBL29323838 | 0.74 | TDP1 (0.46) | MAOAMAOBAOC2CNR2KCNH2 | |
| SCHEMBL16564382 | 0.73 | CNR2 (0.35) | MAOAMAOBAOC2GLP1RCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980353-B | ROR gamma modulators | 领先制药控股公司 | 2019-06-14 | — | — | CN | disclosed |