Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096901 | 0.75 | AOC3 (0.44) | AOC3BRD4NPC1RAB9AHRH4 | |
| SCHEMBL11825755 | 0.74 | AOC3 (0.40) | AOC3BRD4NPC1RAB9AHRH4 | |
| SCHEMBL22021824 | 0.69 | CHRNA7 (0.43) | AOC3BRD4KDM4EMAPTALDH1A1 | |
| SCHEMBL12948668 | 0.68 | FLT3 (0.41) | AOC3BRD4NPC1RAB9AHRH4 | |
| SCHEMBL9608820 | 0.68 | HSD11B1 (0.40) | ALDH1A1 | |
| SCHEMBL7973508 | 0.65 | HRH3 (0.38) | HRH4KDM4EMAPTALDH1A1HRH3 | |
| SCHEMBL27550805 | 0.65 | CYP2A6 (0.49) | AOC3BRD4NPC1RAB9AHRH4 | |
| SCHEMBL6412283 | 0.64 | NR3C1 (0.46) | AOC3HRH4KDM4EMAPTFLT3 | |
| SCHEMBL26659436 | 0.64 | KDM4E (0.36) | AOC3BRD4NPC1RAB9AHRH4 | |
| SCHEMBL7500375 | 0.64 | HRH4 (0.52) | BRD4HRH4HRH3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912579-A | A kind of preparation method of 2,2- disubstituted tetrahydrofuran derivatives | 华中科技大学 | 2019-06-21 | — | — | CN | disclosed |