Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 3/20 | 0.34 |
| ▸ | VCP | P55072 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22021824 | 0.72 | CHRNA7 (0.43) | HRH3CHRNA7KDM4EALDH1A1MAPT | |
| SCHEMBL633353 | 0.72 | SLC6A2 (0.43) | — | |
| SCHEMBL9020233 | 0.71 | RAB9A (0.38) | CHRNA7KDM4EALDH1A1 | |
| SCHEMBL7968110 | 0.71 | HTR6 (0.40) | CHRNA7KDM4EALDH1A1MAPT | |
| SCHEMBL11825755 | 0.69 | AOC3 (0.40) | HRH3HRH4KDM4EALDH1A1MAPT | |
| SCHEMBL7121073 | 0.68 | OPRL1 (0.35) | — | |
| SCHEMBL6096901 | 0.67 | AOC3 (0.44) | HRH4KDM4EALDH1A1MAPT | |
| SCHEMBL21919669 | 0.67 | CYP2A6 (0.36) | HRH3CHRNA7KDM4EALDH1A1MAPT | |
| SCHEMBL7501279 | 0.66 | HTR6 (0.44) | HRH3CHRNA7HRH4VCPALDH1A1 | |
| SCHEMBL4669798 | 0.66 | OPRK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014374-A2 | PROCESSES FOR THE PREPRATION OF EXO- AND ENDO-INDOLOTROPANES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |