SCHEMBL28300029

SCHEMBL28300029

C[Si](C)(c1ccc(C(N)=O)cc1)c1ccc(C(N)=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.64
PARP10 Q53GL7 9/20 0.50
PARP4 Q9UKK3 2/20 0.50
PARP1 P09874 2/20 0.50
CA2 P00918 2/20 0.50
CA1 P00915 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
PARP15 Q460N3 2/20 0.48
ALDH1A1 P00352 1/20 0.48
KMT2A Q03164 1/20 0.48
PARP14 Q460N5 1/20 0.48
PARP16 Q8N5Y8 1/20 0.48
PARP11 Q9NR21 1/20 0.48
TSHR P16473 2/20 0.48
POLB P06746 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 1/20 0.48
CYP2C19 P33261 1/20 0.48
RECQL P46063 1/20 0.48
BLM P54132 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5470502 0.86 PARP10 (0.50) HPGDPARP10PARP4PARP1CA2
Terephthalamide SCHEMBL23774 0.79 PARP1 (0.71) PARP10PARP4PARP1CA2CA1
SCHEMBL3482898 0.78 HPGD (1.00) HPGDCA2CA1ALDH1A1TSHR
SCHEMBL28300032 0.77 PARP10 (0.47) HPGDPARP10PARP4PARP1CA2
SCHEMBL8413865 0.76 HPGD (0.64) HPGDCA2CA1ALDH1A1TSHR
Terephthalamide SCHEMBL689841 0.76 PARP1 (0.67) PARP10PARP4PARP1CA2CA1
Terephthalamide SCHEMBL11512422 0.76 PARP1 (0.67) PARP10PARP4PARP1CA2CA1
Terephthalamide SCHEMBL1087289 0.76 PARP1 (0.67) PARP10PARP4PARP1CA2CA1
Terephthalamide SCHEMBL1906838 0.76 PARP1 (0.67) PARP10PARP4PARP1CA2CA1
Terephthalamide SCHEMBL29102653 0.76 PARP1 (0.67) PARP10PARP4PARP1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104641292-B Photosensitive resin composition for display device insulating film, the display device insulating film using it and the display device using it 第一毛织株式会社 2019-06-18 CN disclosed