Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 2/20 | 0.32 |
| ▸ | ARG2 | P78540 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625145 | 0.76 | — | — | |
| SCHEMBL27850168 | 0.75 | ATM (0.33) | MAOAMAOBGAA | |
| SCHEMBL27680771 | 0.75 | ATM (0.33) | MAOAMAOB | |
| SCHEMBL5969030 | 0.72 | LMNA (0.34) | MAOAMAOB | |
| SCHEMBL785469 | 0.72 | L3MBTL1 (0.36) | EPHX1 | |
| Ethylenediamine SCHEMBL5093336 | 0.72 | ALOX15 (0.36) | MAOAMAOBTDP1GAA | |
| SCHEMBL18834717 | 0.71 | NR1H2 (0.48) | EPHX1 | |
| SCHEMBL6703644 | 0.70 | SSTR4 (0.32) | — | |
| SCHEMBL3571988 | 0.69 | EPHX1 (0.59) | EPHX1 | |
| Piperazine SCHEMBL17912476 | 0.68 | DGAT1 (0.33) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897011-A | A kind of IDO inhibitor and its application | 上海华汇拓医药科技有限公司 | 2019-06-18 | — | — | CN | disclosed |