Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28257149 | 0.90 | LMNA (0.49) | ESR2KDM4ETP53ATMMAPT | |
| SCHEMBL4509505 | 0.82 | CYP11B2 (0.72) | CYP11B1CYP11B2CYP17A1CYP1A2CYP3A4 | |
| SCHEMBL197522 | 0.80 | CA1 (0.79) | ESR2KDM4ETP53MAPTCA12 | |
| SCHEMBL6733562 | 0.80 | CA1 (0.79) | ESR2KDM4ETP53MAPTCA12 | |
| SCHEMBL6682176 | 0.80 | ATM (0.72) | KDM4ETP53ATMMAPTCYP1A2 | |
| SCHEMBL9151672 | 0.80 | CA1 (0.79) | ESR2KDM4ETP53MAPTCA12 | |
| SCHEMBL21960161 | 0.78 | CYP11B1 (0.73) | MAP4K4CYP11B1CYP11B2CYP17A1CYP1A2 | |
| SCHEMBL11396596 | 0.77 | LTA4H (0.54) | KDM4ETP53MAPTCA12CA1 | |
| SCHEMBL21345911 | 0.77 | NPSR1 (0.53) | ATMMAPTCYP2C9NPC1RAB9A | |
| SCHEMBL22778252 | 0.77 | CYP11B2 (0.72) | KDM4EMAPTCYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232025-A1 | PHOSPHINE REAGENTS FOR AZINE FLUOROALKYLATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087129-A9 | PHOSPHINE REAGENTS FOR AZINE FLUOROALKYLATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022087129-A1 | PHOSPHINE REAGENTS FOR AZINE FLUOROALKYLATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-04-28 | — | — | WO | disclosed |
| CN-107207516-B | Octahydro pyrrolo- [3,4-c] azole derivatives and application thereof | 广东东阳光药业有限公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-102014900-B | Method of treating cancer using a neuropeptide Y5R (NPY5R) antagonist | UNIV HEALTH NETWORK | 2014-04-02 | — | — | CN | disclosed |
| CN-102014900-A | Method of treating cancer using a neuropeptide Y5R (NPY5R) antagonist | UNIV HEALTH NETWORK | 2011-04-13 | — | — | CN | disclosed |