Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | TARS1 | P26639 | 2/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247740 | 0.89 | ADORA3 (0.31) | ADORA3ADORA2BADORA1 | |
| SCHEMBL16987222 | 0.85 | TARS1 (0.38) | ADORA1TARS1 | |
| SCHEMBL29435121 | 0.85 | TARS1 (0.38) | ADORA1TARS1 | |
| SCHEMBL28564130 | 0.85 | TARS1 (0.38) | ADORA1TARS1 | |
| SCHEMBL29089525 | 0.75 | TARS1 (0.39) | ADORA1TARS1 | |
| SCHEMBL28494144 | 0.74 | TARS1 (0.36) | ADORA3ADORA2AADORA2BADORA1TARS1 | |
| SCHEMBL31326251 | 0.74 | TARS1 (0.36) | ADORA3ADORA2AADORA2BADORA1TARS1 | |
| SCHEMBL28475028 | 0.73 | SLC29A1 (0.46) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL31406475 | 0.73 | ADORA2A (0.36) | ADORA3ADORA2AADORA2BADORA1TARS1 | |
| SCHEMBL28120771 | 0.73 | TARS1 (0.35) | TARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110446781-A | Donor recovery template multiple gene group editor | BLUEBIRD BIO INC | 2019-11-12 | — | — | CN | disclosed |
| CN-109923211-A | PD-1 HOMING ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE | 蓝鸟生物公司 | 2019-06-21 | — | — | CN | disclosed |