Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL7121208 | 0.98 | TSHR (0.57) | TSHRALDH1A1MAOAMAOBCYP2A6 | |
| Biphenyl SCHEMBL11170240 | 0.92 | TSHR (0.52) | TSHRALDH1A1MAPT | |
| Butane SCHEMBL8909318 | 0.82 | TSHR (0.72) | TSHRALDH1A1MAOAMAOBDRD4 | |
| Butane SCHEMBL2150151 | 0.82 | TSHR (0.63) | TSHRALDH1A1MAOAMAOBCYP2A6 | |
| SCHEMBL27522415 | 0.82 | TSHR (0.93) | TSHRMAOAMAOBCYP2A6DRD4 | |
| Alcohol SCHEMBL1872106 | 0.80 | TSHR (0.60) | TSHRALDH1A1MAOAMAOBCYP2A6 | |
| Alcohol SCHEMBL10885293 | 0.80 | TSHR (0.68) | TSHRALDH1A1MAOAMAOBCYP2A6 | |
| Methoxymethane SCHEMBL28445087 | 0.79 | TSHR (0.77) | TSHRMAOAMAOBCYP2A6DRD4 | |
| SCHEMBL451157 | 0.79 | TSHR (0.86) | TSHRMAOAMAOBCYP2A6DRD4 | |
| SCHEMBL9662 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3763706-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-01-13 | — | — | EP | claimed |
| EP-3453702-A2 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | Merial, Inc. (US) | 2019-03-13 | — | — | EP | claimed |
| US-9359305-B2 | Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof | MERIAL, INC. (US) | 2016-06-07 | — | — | US | claimed |
| US-20150366198-A1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL, INC. (US) | 2015-12-24 | — | — | US | claimed |
| EP-2895465-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | Merial Limited (US) | 2015-07-22 | — | — | EP | claimed |
| US-20150166485-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2015-06-18 | — | — | US | claimed |
| US-20130281392-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2013-10-24 | — | — | US | claimed |
| WO-2013158894-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2013-10-24 | — | — | WO | claimed |
| EP-3763706-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-01-13 | — | — | EP | disclosed |
| US-10251863-B2 | Parasiticidal compositions comprising indole derivatives, methods and uses thereof | MERIAL INC. (US) | 2019-04-09 | — | — | US | disclosed |
| EP-3453702-A2 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | Merial, Inc. (US) | 2019-03-13 | — | — | EP | disclosed |
| US-20170290803-A1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL, INC. (US) | 2017-10-12 | — | — | US | disclosed |
| US-9776986-B2 | Parasiticidal compositions comprising indole derivatives, methods and uses thereof | MERIAL INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9695129-B2 | Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof | MERIAL INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20150166485-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2015-06-18 | — | — | US | disclosed |
| US-9000187-B2 | Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof | MERIAL, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| WO-2013158894-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2013-10-24 | — | — | WO | disclosed |
| US-20130281392-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2013-10-24 | — | — | US | disclosed |
| EP-2188322-A1 | NOVEL ARYLAMINE POLYMER, METHOD FOR PRODUCING THE SAME, INK COMPOSITION, FILM, ELECTRONIC DEVICE, ORGANIC THIN-FILM TRANSISTOR, AND DISPLAY DEVICE | Ricoh Company, Ltd. (JP) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009035133-A1 | NOVEL ARYLAMINE POLYMER, METHOD FOR PRODUCING THE SAME, INK COMPOSITION, FILM, ELECTRONIC DEVICE, ORGANIC THIN-FILM TRANSISTOR, AND DISPLAY DEVICE | RICOH COMPANY, LTD. (JP) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166485-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | LIPC, CYP3A43, CYP51A1 | TSHR 4248/4885ALDH1A1 411/4885MAOA 418/4885 |
| US-20130281392-A1 | PARASITICIDAL COMPOSITIONS COMPRISING BENZIMIDAZOLE DERIVATIVES, METHODS AND USES THEREOF | LIPC, CYP3A43, CYP51A1 | TSHR 4248/4885ALDH1A1 411/4885MAOA 418/4885 |
| US-10251863-B2 | Parasiticidal compositions comprising indole derivatives, methods and uses thereof | IDO1, IDO2, MMP1 | TSHR 2979/4885ALDH1A1 663/4885MAOA 23/4885 |
| US-20170290803-A1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | IDO1, IDO2, MMP1 | TSHR 2979/4885ALDH1A1 663/4885MAOA 23/4885 |
| US-20150366198-A1 | PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF | IDO1, IDO2, MMP1 | TSHR 2979/4885ALDH1A1 663/4885MAOA 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.