Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.44 |
| ▸ | VEGFA | P15692 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714465 | 0.83 | GPR3 (0.45) | GPR3GRIN1GRIN2BGRIN2AALDH1A1 | |
| SCHEMBL14027315 | 0.83 | TBXAS1 (0.46) | TBXAS1EPAS1VEGFASMN1; SMN2SLC6A2 | |
| SCHEMBL16952740 | 0.83 | GPR3 (0.42) | GPR3GRIN1GRIN2BGRIN2AALDH1A1 | |
| SCHEMBL12500157 | 0.81 | SLC6A2 (0.52) | GPR3ALDH1A1MAPTSLC6A2SLC6A4 | |
| SCHEMBL10972329 | 0.81 | MAPT (0.59) | GPR3GRIN1GRIN2BGRIN2AALDH1A1 | |
| SCHEMBL28026110 | 0.80 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2323409 | 0.80 | MAOB (0.48) | GPR3ALDH1A1MAPT | |
| SCHEMBL21268248 | 0.77 | MAPT (0.43) | MRGPRX4GPR3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3105876 | 0.77 | TBXAS1 (0.54) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| Water SCHEMBL27843768 | 0.77 | LMNA (0.49) | GPR3GRIN1GRIN2BGRIN2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952289-A | TRPV4 antagonist | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2019-06-28 | — | — | CN | claimed |
| EP-4735423-A1 | KV7 MODULATORS | Saniona A/S (DK) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025003343-A1 | KV7 MODULATORS | SANIONA A/S (DK) | 2025-01-02 | — | — | WO | disclosed |
| CN-109952289-B | TRPV4 antagonists | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-109952289-A | TRPV4 antagonist | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2019-06-28 | — | — | CN | disclosed |