Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HK1 | P19367 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4473468 | 0.83 | IDO1 (0.50) | SCN9AHCRTR1HCRTR2KAT6AEGFR | |
| SCHEMBL4542718 | 0.83 | PRKCI (0.53) | SCN9AHCRTR1HCRTR2KAT6AFYN | |
| SCHEMBL7855710 | 0.81 | HCRTR1 (0.43) | SCN9AHCRTR1HCRTR2KAT6AEGFR | |
| SCHEMBL7693404 | 0.81 | TAAR1 (0.46) | SCN9AHCRTR1HCRTR2KAT6AEGFR | |
| SCHEMBL5322690 | 0.79 | RAB9A (0.54) | SCN9AKAT6AEGFRALDH1A1MAPT | |
| SCHEMBL1259158 | 0.79 | CARM1 (0.40) | SCN9ACHEK2ALDH1A1MAPTRAB9A | |
| SCHEMBL1879703 | 0.74 | TSHR (0.51) | SCN9AKAT6AALDH1A1MAPTHPGD | |
| SCHEMBL4518536 | 0.74 | CYP19A1 (0.50) | SCN9AKAT6AFYNABL1ATP4A | |
| SCHEMBL10151028 | 0.74 | SCN9A (0.51) | SCN9AKAT6AEGFRALDH1A1ATP4A | |
| SCHEMBL2789456 | 0.74 | HSD17B1 (0.58) | SCN9AKAT6AFYNATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952302-A | Muscarine M1 receptor forward direction allosteric modulators | 苏文生命科学有限公司 | 2019-06-28 | — | — | CN | disclosed |