Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ATP4A | P20648 | 2/20 | 0.44 |
| ▸ | ATP4B | P51164 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30042796 | 1.00 | CYP19A1 (0.50) | CYP19A1SCN9AIDO1METAP2METAP1 | |
| SCHEMBL28327241 | 0.85 | SCN9A (0.49) | CYP19A1SCN9AIDO1METAP2METAP1 | |
| SCHEMBL5322690 | 0.79 | RAB9A (0.54) | SCN9AIDO1METAP2KAT6A | |
| SCHEMBL14060817 | 0.78 | CAMK2D (0.43) | ALOX5ABL1 | |
| SCHEMBL2789456 | 0.78 | HSD17B1 (0.58) | CYP19A1SCN9AMETAP2ATP4AATP4B | |
| SCHEMBL4524263 | 0.78 | KDM4E (0.53) | SCN9AIDO1METAP2METAP1KMO | |
| SCHEMBL30989356 | 0.78 | SCN9A (0.51) | SCN9AIDO1METAP2METAP1ATP4A | |
| SCHEMBL1879703 | 0.78 | TSHR (0.51) | SCN9AMETAP2KAT6A | |
| SCHEMBL7389467 | 0.78 | SCN9A (0.48) | SCN9AIDO1METAP2METAP1KAT6A | |
| SCHEMBL10151028 | 0.78 | SCN9A (0.51) | SCN9AIDO1METAP2METAP1ATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007108566-A1 | PAIN-RELIEVING COMPOSITION | EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-09-27 | — | — | WO | claimed |
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. | 2013-03-07 | — | — | US | disclosed |
| US-20120108614-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC. | 2012-05-03 | — | — | US | disclosed |
| WO-2007108566-A1 | PAIN-RELIEVING COMPOSITION | EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108614-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | CYP19A1 2044/4885SCN9A 1400/4885IDO1 3851/4885 |
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | CYP19A1 1202/4885SCN9A 361/4885IDO1 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.