Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 11/20 | 0.37 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302130 | 0.81 | RORC (0.39) | — | |
| SCHEMBL29287129 | 0.77 | GCK (0.37) | GCKLNPEP | |
| SCHEMBL24774119 | 0.69 | MMP13 (0.41) | GCKELOVL6CDK1CDK2KDR | |
| SCHEMBL11951572 | 0.69 | MCOLN3 (0.51) | GCKELOVL6CNR1MMP13 | |
| SCHEMBL20636299 | 0.68 | CA2 (0.40) | GCKMMP13 | |
| SCHEMBL29287130 | 0.68 | CA2 (0.40) | GCKMMP13 | |
| SCHEMBL28243703 | 0.67 | NPC1 (0.41) | — | |
| SCHEMBL28100811 | 0.66 | POLB (0.33) | — | |
| SCHEMBL29220569 | 0.66 | MMP13 (0.41) | GCKELOVL6CNR1MMP13 | |
| SCHEMBL184640 | 0.65 | GCK (0.50) | GCKELOVL6MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952298-A | Indole carboxamides analog derivative, preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2019-06-28 | — | — | CN | disclosed |