Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638075 | 0.89 | SLC18A3 (0.43) | MEN1KMT2ACYP2C9PRCPSLC18A3 | |
| SCHEMBL1639225 | 0.89 | SLC18A3 (0.43) | MEN1KMT2ACYP2C9PRCPSLC18A3 | |
| SCHEMBL451612 | 0.89 | SLC18A3 (0.43) | MEN1KMT2ACYP2C9PRCPSLC18A3 | |
| SCHEMBL8193202 | 0.87 | SLC18A3 (0.47) | MEN1KMT2ASMN1; SMN2PRCPSLC18A3 | |
| SCHEMBL8804137 | 0.85 | RECQL (0.39) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL9592443 | 0.84 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL38661306 | 0.84 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| Pyridine SCHEMBL28226947 | 0.81 | LMNA (0.37) | MEN1KMT2APOLBSMN1; SMN2RECQL | |
| Piperidine SCHEMBL27283393 | 0.81 | SLC18A3 (0.41) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL8220636 | 0.79 | CTSL (0.46) | MEN1KMT2ABMPR1BPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810047-A | (R) synthetic method of the chiral intermediate of -3- Phenylpiperidine or/and (S) -3- Phenylpiperidine and Ni Lapani | 上海博邦医药科技有限公司 | 2019-05-28 | — | — | CN | disclosed |