SCHEMBL28303263

SCHEMBL28303263

Cc1ccc(S(=O)(=O)n2ccnc2-c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.54
NR1H2 P55055 1/20 0.54
NR1H3 Q13133 1/20 0.54
POLB P06746 1/20 0.52
ALDH3A1 P30838 1/20 0.52
HTT P42858 1/20 0.52
NOD1 Q9Y239 1/20 0.52
RAPGEF4 Q8WZA2 1/20 0.51
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
ALDH1A1 P00352 3/20 0.48
MAPT P10636 2/20 0.48
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
GAA P10253 2/20 0.46
TSHR P16473 2/20 0.45
HSD11B1 P28845 2/20 0.45
NPSR1 Q6W5P4 2/20 0.44
MCOLN3 Q8TDD5 1/20 0.44
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL770698 0.94 L3MBTL1 (0.50) L3MBTL1NR1H2NR1H3POLBALDH3A1
SCHEMBL723626 0.90 MET (0.51) L3MBTL1NR1H2NR1H3HTTALDH1A1
SCHEMBL28219334 0.86 MEN1 (0.50) L3MBTL1HTTALDH1A1MAPTLMNA
SCHEMBL28219756 0.86 PKM (0.52) NR1H2NR1H3ALDH3A1RAPGEF4ALDH1A1
SCHEMBL9089850 0.84 L3MBTL1 (0.48) L3MBTL1NR1H2NR1H3POLBALDH3A1
SCHEMBL14545885 0.80 RECQL (0.56) L3MBTL1POLBALDH3A1HTTNOD1
SCHEMBL15902658 0.80 MEN1 (0.47) L3MBTL1HTTALDH1A1MAPTLMNA
SCHEMBL724292 0.80 PKM (0.49) NR1H2NR1H3ALDH3A1HTTRAPGEF4
SCHEMBL18040300 0.80 ALDH3A1 (0.48) ALDH3A1HTTALDH1A1MAPTLMNA
SCHEMBL18040302 0.80 MEN1 (0.51) L3MBTL1POLBHTTRAPGEF4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108129478-B A kind of copper process for catalytic synthesis of organic sulphones and application 曲阜师范大学 2019-07-09 CN disclosed