Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28012008 | 0.77 | HPGD (0.51) | HPGDOPRM1OPRK1OPRL1HRH1 | |
| SCHEMBL10447019 | 0.72 | ALDH1A1 (0.50) | HPGDHRH1MEN1KMT2A | |
| SCHEMBL14663958 | 0.71 | HPGD (0.45) | HPGDOPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL4656372 | 0.70 | NOTUM (0.49) | HPGDOPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL4200813 | 0.70 | NOTUM (0.51) | HPGDOPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL22401875 | 0.69 | NOTUM (0.44) | HPGDOPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL21142478 | 0.68 | NOTUM (0.46) | HPGDOPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL4656369 | 0.67 | HTR7 (0.57) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL3227444 | 0.67 | NOTUM (0.49) | HPGDOPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL8669245 | 0.67 | HPGD (0.44) | HPGDOPRM1OPRK1OPRL1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879789-A | A kind of preparation method of substituted indole ketones derivant | 贵州医科大学 | 2019-06-14 | — | — | CN | disclosed |