Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302854 | 0.74 | DPP4 (0.45) | NR4A2DPP4BACE1NOTUM | |
| SCHEMBL5154427 | 0.72 | NR4A2 (0.68) | LMNAADORA2AIKBKBSMN1; SMN2KDM4E | |
| SCHEMBL26645797 | 0.69 | NPC1 (0.48) | LMNAADORA2AIKBKBRAB9ASMN1; SMN2 | |
| SCHEMBL24071140 | 0.68 | PTPN1 (0.42) | ADORA2AIKBKBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13170400 | 0.68 | RAB9A (0.74) | IKBKBRAB9ASMN1; SMN2NPC1CASP3 | |
| SCHEMBL6352038 | 0.67 | ADORA2A (0.56) | LMNAADORA2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7709062 | 0.67 | BACE1 (0.57) | ADORA2AIKBKBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3243767 | 0.67 | LMNA (0.47) | LMNAADORA2AIKBKBRAB9ASMN1; SMN2 | |
| SCHEMBL28902429 | 0.67 | MPL (0.55) | LMNAADORA2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL2324859 | 0.67 | CSNK1A1 (0.56) | LMNAADORA2ARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041285-A | The preparation method of 2,4,5- of one kind, tri- substituted oxazoline class compound | 大连理工大学 | 2019-07-23 | — | — | CN | disclosed |