Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034055 | 0.82 | LMNA (0.49) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL28874126 | 0.81 | L3MBTL1 (0.45) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL28622105 | 0.81 | ALDH1A1 (0.48) | NPC1RAB9AALDH1A1FFAR1MEN1 | |
| SCHEMBL6443036 | 0.77 | NPC1 (0.51) | NPC1RAB9AALDH1A1FFAR1MEN1 | |
| SCHEMBL19583686 | 0.76 | HTT (0.51) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7508153 | 0.73 | ALDH1A1 (0.51) | NPC1RAB9AKDM4EALDH1A1FFAR1 | |
| SCHEMBL1695235 | 0.73 | NPC1 (0.66) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL3388330 | 0.73 | ALDH1A1 (0.55) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| Acetic Acid SCHEMBL23429845 | 0.72 | HRH3 (0.56) | NPC1KDM4EALDH1A1POLBHTT | |
| SCHEMBL20280457 | 0.72 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956900-A | Compound and pharmaceutical composition comprising it | 财团法人工业技术研究院 | 2019-07-02 | — | — | CN | disclosed |