Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL28312143 | 0.84 | CES2 (0.61) | CES2CES1ALDH1A1ALOX15MDM2 | |
| SCHEMBL343535 | 0.82 | CES2 (0.68) | CES2CES1ALDH1A1ALOX15MDM2 | |
| SCHEMBL20472214 | 0.78 | MEN1 (0.51) | ALDH1A1MEN1HPGDKMT2ANPSR1 | |
| SCHEMBL18861017 | 0.77 | MCL1 (0.52) | RARBRARA | |
| SCHEMBL18861020 | 0.77 | PTPN11 (0.53) | TSHR | |
| SCHEMBL28672289 | 0.75 | TSHR (0.49) | CES2CES1ALDH1A1ALOX15MEN1 | |
| SCHEMBL15037828 | 0.74 | CES2 (0.53) | CES2CES1ALDH1A1HTR7MDM2 | |
| SCHEMBL29127613 | 0.74 | CES2 (0.53) | CES2CES1ALDH1A1HTR7MDM2 | |
| SCHEMBL29406527 | 0.74 | CES2 (0.53) | CES2CES1ALDH1A1HTR7MDM2 | |
| SCHEMBL28062364 | 0.74 | HTR7 (0.59) | CES2CES1ALDH1A1HTR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764514-B | Aminopyridine derivatives as inhibitors of TAM family kinases | 圣诺康生命科学公司 | 2019-07-12 | — | — | CN | disclosed |