Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22625286 | 0.84 | LCK (0.66) | LCKMAPTKMT2APKMUSP2 | |
| SCHEMBL30381384 | 0.82 | MAPT (0.63) | LCKMAPTKMT2APKMUSP2 | |
| SCHEMBL677432 | 0.78 | MAPT (0.62) | LCKMAPTKMT2APKMUSP2 | |
| SCHEMBL4165022 | 0.76 | NR3C1 (0.45) | MAPTKMT2APKMALDH1A1MEN1 | |
| SCHEMBL30381697 | 0.76 | LCK (0.56) | LCKMAPTKMT2APKMUSP2 | |
| SCHEMBL7147011 | 0.76 | PARP1 (0.62) | LCKMAPTKMT2APKMUSP2 | |
| SCHEMBL20299501 | 0.76 | LCK (0.56) | LCKMAPTKMT2APKMUSP2 | |
| SCHEMBL3372898 | 0.76 | LCK (0.56) | LCKMAPTKMT2APKMUSP2 | |
| SCHEMBL22625287 | 0.76 | CSNK2A2 (0.59) | LCKMAPTKMT2APKMUSP2 | |
| SCHEMBL30381597 | 0.76 | PARP1 (0.62) | LCKMAPTKMT2APKMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028407-A | A kind of method preparing -1 ', 3 '-dione compounds of spiral shell [cyclopropane -1,2 '-indenes] | 苏州大学 | 2019-07-19 | — | — | CN | disclosed |