Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 16/20 | 0.63 |
| ▸ | HTR1A | P08908 | 15/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28231884 | 0.91 | HTR3A (0.71) | HTR3AHTR1AHTR2CHTR3EHTR3B | |
| SCHEMBL546686 | 0.83 | HTR3A (0.81) | HTR3AHTR1AHTR2CHTR3EHTR3B | |
| SCHEMBL546581 | 0.82 | HTR3A (0.67) | HTR3AHTR1AHTR2CHTR3EHTR3B | |
| SCHEMBL27550397 | 0.76 | HTR1A (0.71) | HTR3AHTR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL546511 | 0.76 | HTR3A (1.00) | HTR3AHTR1AHTR2CHTR3EHTR3B | |
| Tert-Butyl Formate SCHEMBL28112175 | 0.76 | HTR1A (0.43) | HTR3AHTR1AHTR2CCYP1A2CYP3A4 | |
| SCHEMBL27568938 | 0.75 | HTR1A (0.67) | HTR3AHTR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17260217 | 0.73 | HTR3E (0.62) | HTR3AHTR1AHTR2CHTR3EHTR3B | |
| SCHEMBL28254187 | 0.72 | HTR3A (0.71) | HTR3AHTR1AHTR2CHTR3EHTR3B | |
| SCHEMBL547373 | 0.72 | HTR3A (0.71) | HTR3AHTR1AHTR2CHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110022869-A | For skin and/or the serotonin 1B receptor stimulators of hair reparation | 巴斯德研究院 | 2019-07-16 | — | — | CN | disclosed |
| CN-108348486-A | 5-hydroxytryptamine 1B receptor agonists as promoters for satellite cell self-renewal and/or differentiation | 巴斯德研究院 | 2018-07-31 | — | — | CN | disclosed |