Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.85 |
| ▸ | HTR2A | P28223 | 7/20 | 0.85 |
| ▸ | HTR1A | P08908 | 6/20 | 0.85 |
| ▸ | HTR7 | P34969 | 5/20 | 0.85 |
| ▸ | TSHR | P16473 | 4/20 | 0.85 |
| ▸ | HTR1B | P28222 | 4/20 | 0.85 |
| ▸ | HTR1D | P28221 | 4/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.85 |
| ▸ | HTR2B | P41595 | 3/20 | 0.85 |
| ▸ | HTR5A | P47898 | 3/20 | 0.85 |
| ▸ | HTR6 | P50406 | 3/20 | 0.85 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.85 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.85 |
| ▸ | HTR1E | P28566 | 2/20 | 0.85 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.85 |
| ▸ | HTR3B | O95264 | 1/20 | 0.85 |
| ▸ | DRD1 | P21728 | 1/20 | 0.85 |
| ▸ | HTR1F | P30939 | 1/20 | 0.85 |
| ▸ | DRD3 | P35462 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serotonin SCHEMBL5833418 | 0.94 | HTR2C (0.85) | HTR2CHTR2AHTR1AHTR7TSHR | |
| Serotonin SCHEMBL29165023 | 0.93 | HTR2C (0.83) | HTR2CHTR2AHTR1AHTR7TSHR | |
| Serotonin SCHEMBL28466208 | 0.93 | HTR2C (0.83) | HTR2CHTR2AHTR1AHTR7TSHR | |
| Serotonin SCHEMBL183226 | 0.92 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR7TSHR | |
| Serotonin SCHEMBL30057954 | 0.92 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR7TSHR | |
| Serotonin SCHEMBL29349412 | 0.92 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR7TSHR | |
| Serotonin SCHEMBL1495 | 0.92 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR7TSHR | |
| Serotonin SCHEMBL25341783 | 0.91 | HTR2C (1.00) | HTR2CHTR2AHTR1AHTR7TSHR | |
| Serotonin SCHEMBL1675866 | 0.91 | HTR2C (0.97) | HTR2CHTR2AHTR1AHTR7TSHR | |
| Serotonin SCHEMBL3091827 | 0.91 | HTR2C (0.97) | HTR2CHTR2AHTR1AHTR7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041318-B | Dopamine D5 receptor agonist and preparation and application thereof | 中国科学院上海药物研究所 | 2022-07-29 | — | — | CN | claimed |
| CN-110041318-A | A kind of Human Dopamine D 5 Receptor agonist and its preparation and application | 中国科学院上海药物研究所 | 2019-07-23 | — | — | CN | claimed |
| CN-110041318-B | Dopamine D5 receptor agonist and preparation and application thereof | 中国科学院上海药物研究所 | 2022-07-29 | — | — | CN | disclosed |
| CN-110041318-B | Dopamine D5 receptor agonist and preparation and application thereof | 中国科学院上海药物研究所 | 2022-07-29 | — | — | CN | disclosed |
| CN-110041318-A | A kind of Human Dopamine D 5 Receptor agonist and its preparation and application | 中国科学院上海药物研究所 | 2019-07-23 | — | — | CN | disclosed |
| CN-110041318-A | A kind of Human Dopamine D 5 Receptor agonist and its preparation and application | 中国科学院上海药物研究所 | 2019-07-23 | — | — | CN | disclosed |