Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394827 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1HPSE | |
| SCHEMBL76069 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1HPSE | |
| SCHEMBL22597948 | 0.80 | POLB (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1HPSE | |
| SCHEMBL17973539 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1HPSE | |
| SCHEMBL17839910 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1HPSE | |
| SCHEMBL4576394 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1HPSE | |
| SCHEMBL18507798 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1HPSE | |
| SCHEMBL6256744 | 0.76 | NPC1 (0.37) | SMN1; SMN2NPC1RAB9AALDH1A1POLB | |
| SCHEMBL1058740 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1HPSE | |
| SCHEMBL6254890 | 0.74 | GPR139 (0.39) | SMN1; SMN2NPC1RAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736567-B | Antibodies to aripiprazole haptens and uses thereof | 詹森药业有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-110054694-A | The antibody and application thereof of Aripiprazole haptens | 詹森药业有限公司 | 2019-07-26 | — | — | CN | disclosed |