Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76069 | 0.82 | SMN1; SMN2 (0.49) | GPR139MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29394827 | 0.82 | SMN1; SMN2 (0.49) | GPR139MEN1KMT2ASMN1; SMN2MAPT | |
| Benzotriazole SCHEMBL28307173 | 0.74 | SMN1; SMN2 (0.42) | GPR139MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL22597948 | 0.73 | POLB (0.43) | GPR139KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL17973539 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2ATDP1SMN1; SMN2MAPT | |
| SCHEMBL4576394 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL266156 | 0.70 | TSHR (0.48) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL17950441 | 0.70 | GPR139 (0.44) | GPR139MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL17839910 | 0.68 | ALDH1A1 (0.49) | MEN1KMT2ATDP1SMN1; SMN2MAPT | |
| SCHEMBL18507798 | 0.67 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007634-A1 | 3-HYDROXY-4-OXO-1,2,3-TRIAZINES AND DERIVATIVES THEREOF FOR AMIDE AND ESTER BOND FORMATION | FRUTAROM LTD. (IL) | 2005-01-27 | — | — | WO | claimed |