SCHEMBL1058740

SCHEMBL1058740

CCP(=O)(CC)On1nnc2ccccc2c1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
SMN1; SMN2 Q16637 4/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
NPC1 O15118 5/20 0.45
RAB9A P51151 5/20 0.45
LMNA P02545 3/20 0.45
MAPT P10636 3/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
HPSE Q9Y251 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30861605 0.83 MEN1 (0.52) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1
SCHEMBL76069 0.83 SMN1; SMN2 (0.49) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1
SCHEMBL29394827 0.83 SMN1; SMN2 (0.49) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1
SCHEMBL17839910 0.83 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1
SCHEMBL17973539 0.82 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1
SCHEMBL18507798 0.81 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1
SCHEMBL17391071 0.81 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1
SCHEMBL10284047 0.79 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1
SCHEMBL4576394 0.79 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1
SCHEMBL757021 0.77 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CYP1A2CYP2C19NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622991-A2 SYNTHESIS OF A CYCLIC PEPTIDE Janssen Pharmaceutica NV (BE) 2025-10-01 EP claimed
EP-4619408-A1 THE SYNTHESIS OF OMAPATRILAT Endothelium Scanning Nanotechnology Limited (AU) 2025-09-24 EP claimed
US-12215114-B2 Processes and intermediates for producing diazaspiro lactam compounds NAUREX INC. (US) 2025-02-04 US claimed
EP-4472948-A2 NICOTINATE AND NICOTINAMIDE RIBOSIDE-BASED COMPOUNDS AND DERIVATIVES THEREOF New Frontier Bio, Inc. (US) 2024-12-11 EP claimed
CN-118613472-A Nicotinamide ester and nicotinamide riboside-based compounds and derivatives thereof 新前沿生物公司 2024-09-06 CN claimed
EP-3986400-B1 PROCESSES AND INTERMEDIATES FOR PRODUCING DIAZASPIRO LACTAM COMPOUNDS NAUREX INC (US) 2024-08-21 EP claimed
US-20240269640-A1 METHODS AND COMPOSITIONS FOR LARGE-SCALE CONJUGATABLE POLYMER AND PROTEIN SYNTHESIS Ligandal, Inc. 2024-08-15 US claimed
WO-2024110477-A2 SYNTHESIS OF A CYCLIC PEPTIDE JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 WO claimed
WO-2024103123-A1 THE SYNTHESIS OF OMAPATRILAT Endothelium Scanning Nanotechnology Limited (AU) 2024-05-23 WO claimed
EP-4329931-A1 METHODS AND COMPOSITIONS FOR LARGE-SCALE CONJUGATABLE POLYMER AND PROTEIN SYNTHESIS Ligandal, Inc. (US) 2024-03-06 EP claimed
US-9308479-B2 Cross-linked carbon nanotube networks THE BIO NANO CENTRE LIMITED (GB) 2016-04-12 US claimed
EP-2872500-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF DABIGATRAN ETEXILATE MESYLATE AND ITS INTERMEDIATES THEREOF Rao, Davuluri Ramamohan (IN) 2015-05-20 EP claimed
US-20150122800-A1 CROSS-LINKED GRAPHENE NETWORKS KING ABDULAZIZ UNIVERSITY (SA) 2015-05-07 US claimed
EP-2822893-A2 CROSS-LINKED GRAPHENE NETWORKS The Bio Nano Centre Limited (GB) 2015-01-14 EP claimed
WO-2014009966-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF DABIGATRAN ETEXILATE MESYLATE AND ITS INTERMEDIATES THEREOF RAO DAVULURI RAMAMOHAN (IN) 2014-01-16 WO claimed
EP-2665552-A2 CROSS-LINKED CARBON NANOTUBE NETWORKS Bio Nano Consulting (GB) 2013-11-27 EP claimed
WO-2013132259-A1 GRAPHENE AND GRAPHENE OXIDE AEROGELS/XEROGELS FOR CO2 CAPTURE BIO NANO CONSULTING (GB) 2013-09-12 WO claimed
WO-2013132260-A2 CROSS-LINKED GRAPHENE NETWORKS BIO NANO CONSULTING (GB) 2013-09-12 WO claimed
WO-2013093520-A2 HEATABLE CARBON NANOTUBE AEROGELS, XEROGELS AND GELS BIO NANO CONSULTING (GB) 2013-06-27 WO claimed
WO-2012098345-A2 CROSS-LINKED CARBON NANOTUBE NETWORKS BIO NANO CONSULTING (GB) 2012-07-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215114-B2 Processes and intermediates for producing diazaspiro lactam compounds DDO, DHPS, PGLS ALDH1A1 3004/4885SMN1; SMN2 2645/4885CYP1A2 1138/4885
US-20150122800-A1 CROSS-LINKED GRAPHENE NETWORKS MACF1, MTCL3, GIGYF2 ALDH1A1 2306/4885SMN1; SMN2 4416/4885CYP1A2 485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.