Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054835 | 0.63 | ALDH1A1 (0.32) | HTTPOLBMAPT | |
| SCHEMBL3054833 | 0.60 | PGK1 (0.41) | HTTPOLBMAPT | |
| SCHEMBL11734474 | 0.59 | POLB (0.46) | HTTPOLBMAPT | |
| SCHEMBL22696464 | 0.59 | GRIN2D (0.41) | HTTPOLBMAPT | |
| SCHEMBL24759678 | 0.58 | NOS3 (0.39) | — | |
| SCHEMBL11859386 | 0.57 | TSHR (0.37) | HTTPOLBMAPT | |
| SCHEMBL28879241 | 0.57 | HTT (0.43) | HTTPOLBMAPT | |
| SCHEMBL15431038 | 0.57 | NOS3 (0.32) | — | |
| SCHEMBL27674722 | 0.56 | ALDH1A1 (0.36) | HTTPOLBMAPT | |
| SCHEMBL21027636 | 0.56 | TNKS2 (0.44) | HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |