Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306176 | 0.70 | KMT2A (0.37) | KMT2AMAPTNPSR1TDP1ALDH1A1 | |
| SCHEMBL10799613 | 0.70 | CYP1A2 (0.42) | KMT2AKDM4EMAPTNPSR1TDP1 | |
| SCHEMBL16284293 | 0.69 | CYP1A2 (0.51) | KMT2AMAPTNPSR1TDP1ALDH1A1 | |
| SCHEMBL28128795 | 0.69 | ALDH1A1 (0.44) | KDM4EMAPTTDP1ALDH1A1LMNA | |
| SCHEMBL3962873 | 0.68 | P2RX3 (0.49) | KMT2A | |
| SCHEMBL4382927 | 0.68 | P2RX3 (0.49) | KMT2A | |
| SCHEMBL27864585 | 0.68 | ALDH1A1 (0.62) | KMT2AMAPTTDP1ALDH1A1LMNA | |
| SCHEMBL10780753 | 0.68 | CTSB (0.41) | TYRKMT2AKDM4EMAPTNPSR1 | |
| SCHEMBL2578922 | 0.67 | ATM (0.39) | MAPTTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10774564 | 0.67 | TSHR (0.44) | TYRKMT2AMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |