Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307340 | 0.83 | MAPT (0.39) | KMT2AMAPTMEN1TDP1NPY1R | |
| SCHEMBL28306200 | 0.78 | GLP1R (0.33) | KMT2AMAPTMEN1TDP1NPY1R | |
| SCHEMBL28306191 | 0.75 | MAPT (0.33) | KMT2AMAPTMEN1TDP1MGMT | |
| SCHEMBL28306175 | 0.72 | MAPT (0.43) | KMT2AMAPTTDP1SMN1; SMN2MGMT | |
| SCHEMBL28307339 | 0.72 | MAPT (0.38) | KMT2AMAPTMEN1TDP1SMN1; SMN2 | |
| SCHEMBL5029733 | 0.72 | MGMT (0.41) | KMT2AMAPTMEN1SMN1; SMN2CYP3A4 | |
| SCHEMBL28307347 | 0.70 | TYR (0.36) | KMT2ADCTPP1MAPTMEN1TDP1 | |
| SCHEMBL28307341 | 0.70 | HTT (0.45) | MAPTTDP1NPY1RSMN1; SMN2MGMT | |
| SCHEMBL28306205 | 0.67 | KMT2A (0.35) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL28307335 | 0.67 | HTT (0.38) | MAPTTDP1NPY1RSMN1; SMN2MGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-109970633-A | Pyridine sulfone and its derivative, preparation method and application | 湖南化工研究院有限公司 | 2019-07-05 | — | — | CN | disclosed |