Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306356 | 0.87 | SDHB (0.35) | SDHBNPC1RAB9APDE2APDE3A | |
| SCHEMBL28307456 | 0.83 | SDHB (0.43) | SDHBPDE2APDE3AKMT2ALMNA | |
| SCHEMBL20985660 | 0.80 | SDHB (0.63) | SDHB | |
| SCHEMBL28307435 | 0.78 | SDHB (0.33) | SDHBPDE2APDE3AKMT2ALMNA | |
| SCHEMBL28306419 | 0.78 | SDHB (0.46) | SDHBKMT2ALMNAHPGDNPSR1 | |
| SCHEMBL28307434 | 0.75 | SDHB (0.63) | SDHBKMT2ALMNAHPGDNPSR1 | |
| SCHEMBL28306456 | 0.75 | SDHB (0.64) | SDHBKMT2ALMNAHPGDNPSR1 | |
| SCHEMBL28306444 | 0.75 | SDHB (0.54) | SDHBKMT2ALMNAHPGDNPSR1 | |
| SCHEMBL28910510 | 0.74 | TP53 (0.39) | SDHBKMT2ALMNAHPGDKDM4E | |
| SCHEMBL28306340 | 0.73 | TP53 (0.37) | PDE2APDE3AKMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |