Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | PTPRC | P08575 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31635262 | 0.86 | L3MBTL1 (0.69) | L3MBTL1HTTALDH1A1HPGDPTPRC | |
| SCHEMBL6663354 | 0.83 | MEN1 (0.53) | L3MBTL1HTTALDH1A1HPGDMEN1 | |
| SCHEMBL28746319 | 0.83 | L3MBTL1 (0.61) | L3MBTL1HTTALDH1A1HPGDPTPRC | |
| SCHEMBL28746329 | 0.81 | L3MBTL1 (0.59) | L3MBTL1HTTALDH1A1HPGDPTPRC | |
| SCHEMBL1355675 | 0.81 | L3MBTL1 (0.58) | L3MBTL1HTTALDH1A1HPGDPTPRC | |
| SCHEMBL13529755 | 0.81 | HDAC8 (0.64) | L3MBTL1HTTALDH1A1HPGDPTPRC | |
| SCHEMBL1797542 | 0.81 | L3MBTL1 (0.67) | L3MBTL1HTTALDH1A1HPGDPTPRC | |
| SCHEMBL7308833 | 0.80 | L3MBTL1 (0.58) | L3MBTL1HTTALDH1A1HPGDPTPRC | |
| SCHEMBL15874435 | 0.80 | L3MBTL1 (0.51) | L3MBTL1HDAC8MEN1KMT2AHDAC3 | |
| SCHEMBL541048 | 0.80 | LMNA (0.68) | L3MBTL1ALDH1A1PTPRCHDAC8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228087-B1 | ANTIBODY CATALYSIS OF ENANTIO- AND DIASTEREO-SELECTIVE ALDOL REACTIONS | SCRIPPS RESEARCH INST (US) | 2010-06-09 | — | — | EP | disclosed |
| EP-1228087-B1 | ANTIBODY CATALYSIS OF ENANTIO- AND DIASTEREO-SELECTIVE ALDOL REACTIONS | SCRIPPS RESEARCH INST (US) | 2010-06-09 | — | — | EP | disclosed |
| US-7666658-B1 | Antibody catalysis of enantio- and diastereo-selective aldol reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-23 | — | — | US | disclosed |
| US-7666658-B1 | Antibody catalysis of enantio- and diastereo-selective aldol reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-23 | — | — | US | disclosed |
| US-7666658-B1 | Antibody catalysis of enantio- and diastereo-selective aldol reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-23 | — | — | US | disclosed |
| EP-1228087-A4 | ANTIBODY CATALYSIS OF ENANTIO- AND DIASTEREO-SELECTIVE ALDOL REACTIONS | SCRIPPS RESEARCH INST (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1228087-A1 | ANTIBODY CATALYSIS OF ENANTIO- AND DIASTEREO-SELECTIVE ALDOL REACTIONS | The Scripps Research Institute (US) | 2002-08-07 | — | — | EP | disclosed |
| US-6309881-B2 | ALDEHYDE AND KETONE REACTANTS ARE CONTACTED WITH ANTIBODY MOLECULES OR MOLECULES CONTAINING ANTIBODY COMBINING SITE PORTIONS THAT CATALYZE AN ALDOL ADDITION REACTION | THE SCRIPPS RESEARCH INSTITUTE | 2001-10-30 | — | — | US | disclosed |
| US-20010018201-A1 | Antibody catalysis of enantio- and diastereo-selective aldol reactions | BARBAS CARLOS F (US) | 2001-08-30 | — | — | US | disclosed |
| WO-2001027145-A1 | ANTIBODY CATALYSIS OF ENANTIO- AND DIASTEREO-SELECTIVE ALDOL REACTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-04-19 | — | — | WO | disclosed |
| US-6210938-B1 | CONTACTING ALDEHYDE AND KETONE REACTANTS WITH CATALYTIC ANTIBODIES PRODUCED BY IMMUNIZING SUBJECT WITH STERILE SOLUTION OF ALDOL TRANSITION STATE IMMUNOCONJUGATE INCLUDING A SULFONE BETA-DIKETONE HAPTEN | THE SCRIPPS RESEARCH INSTITUTE | 2001-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010018201-A1 | Antibody catalysis of enantio- and diastereo-selective aldol reactions | ALDOA, DERA, ADH1C | L3MBTL1 1908/4885HTT 3537/4885ALDH1A1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.