Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28307652

N.N#CC(F)c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
TRPA1 O75762 1/20 0.50
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
HPGD P15428 2/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
USP2 O75604 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
DPP4 P27487 2/20 0.36
F2 P00734 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C1 Q04828 1/20 0.34
PBRM1 Q86U86 1/20 0.34
MAP2K1 Q02750 1/20 0.34
ALPG P10696 1/20 0.34
ACSS2 Q9NR19 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1323137 0.97 TSHR (0.52) TSHRTRPA1ALDH1A1LMNAHPGD
SCHEMBL10159567 0.97 TSHR (0.52) TSHRTRPA1ALDH1A1LMNAHPGD
SCHEMBL29261466 0.84 CHRNB2 (0.42) TSHRTRPA1ALDH1A1
SCHEMBL7958219 0.75 LMNA (0.47) ALDH1A1LMNAHPGDHTTSMN1; SMN2
SCHEMBL3984010 0.73 CHRNA7 (0.44) ALDH1A1LMNAHTTSMN1; SMN2L3MBTL1
SCHEMBL19946014 0.73 ESR1 (0.60) ALDH1A1LMNAHPGDSMN1; SMN2
SCHEMBL27961334 0.73 CYP2A6 (0.38) TRPA1ALDH1A1HPGDSMN1; SMN2
SCHEMBL444030 0.73 TSHR (0.46) TSHRALDH1A1LMNAHPGDHTT
SCHEMBL4339266 0.73 SLC6A2 (0.39) TSHRALDH1A1LMNASMN1; SMN2DPP4
SCHEMBL3556521 0.73 HDAC4 (0.42) TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912439-A Method for continuously and rapidly preparing DL-phenylglycine and analogue thereof by using cyanohydrin method 禄丰天宝磷化工有限公司 2019-06-21 CN disclosed