SCHEMBL10159567

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1323137	1.00	TSHR (0.52)	TSHRTRPA1ALDH1A1LMNAHPGD
	Ammonia Solution, Strong SCHEMBL28307652	0.97	TSHR (0.50)	TSHRTRPA1ALDH1A1LMNAHPGD
	SCHEMBL29261466	0.86	CHRNB2 (0.42)	TSHRTRPA1ALDH1A1
	SCHEMBL7958219	0.77	LMNA (0.47)	ALDH1A1LMNAHPGDHTTSMN1; SMN2
	SCHEMBL3984010	0.75	CHRNA7 (0.44)	ALDH1A1LMNAHTTSMN1; SMN2L3MBTL1
	SCHEMBL444030	0.75	TSHR (0.46)	TSHRALDH1A1LMNAHPGDHTT
	SCHEMBL27961334	0.75	CYP2A6 (0.38)	TRPA1ALDH1A1HPGDSMN1; SMN2
	SCHEMBL19946014	0.75	ESR1 (0.60)	ALDH1A1LMNAHPGDSMN1; SMN2
	SCHEMBL4339266	0.75	SLC6A2 (0.39)	TSHRALDH1A1LMNASMN1; SMN2DPP4
	SCHEMBL3556521	0.75	HDAC4 (0.42)	TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.