SCHEMBL28308308

SCHEMBL28308308

CCCC(N)(CCC(C)C)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
THRB P10828 1/20 0.42
KMT2A Q03164 1/20 0.42
ARG2 P78540 10/20 0.37
ARG1 P05089 9/20 0.37
ODC1 P11926 1/20 0.33
FDPS P14324 1/20 0.33
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11143931 0.86 MEN1 (0.59) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL348479 0.85 MEN1 (0.54) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL31001155 0.78 ARG2 (0.44) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL23010905 0.77 ARG1 (0.48) MEN1ALDH1A1CYP1A2THRBKMT2A
3-Methylbutanoic Acid SCHEMBL27489683 0.77 ARG2 (0.42) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL6759254 0.76 MEN1 (0.68) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL6759253 0.76 MEN1 (0.68) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL24163861 0.76 MEN1 (0.68) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL1399007 0.75 ALDH1A1 (0.73) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL20156725 0.75 ARG2 (0.52) MEN1ALDH1A1CYP1A2THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109890852-A Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2019-06-14 CN disclosed