Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.50 |
| ▸ | F10 | P00742 | 5/20 | 0.50 |
| ▸ | DPP4 | P27487 | 4/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922906 | 0.81 | MEN1 (0.52) | F2F10PPARGPPARAMAPT | |
| SCHEMBL19922886 | 0.79 | SMN1; SMN2 (0.47) | F2F10PPARGPPARAMAPT | |
| SCHEMBL22282956 | 0.78 | MAPT (0.52) | F2F10PPARGPPARAMAPT | |
| SCHEMBL19922926 | 0.75 | ALOX15 (0.53) | DPP4PPARGPPARAKDM4EALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL28399259 | 0.74 | SMN1; SMN2 (0.58) | DPP4MAPTKDM4EALDH1A1POLB | |
| SCHEMBL11119802 | 0.74 | AOC3 (0.47) | PPARGPPARAGAAMEN1KMT2A | |
| SCHEMBL6049943 | 0.73 | EPHX2 (0.45) | PPARGPPARAMAPTKDM4EALDH1A1 | |
| SCHEMBL30849662 | 0.73 | CNR2 (0.48) | PPARGPPARAALDH1A1POLBGAA | |
| SCHEMBL1504155 | 0.72 | ALDH1A1 (0.44) | PPARAMAPTKDM4EALDH1A1POLB | |
| SCHEMBL30935351 | 0.72 | ALDH1A1 (0.44) | PPARAMAPTKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072858-A | Indole derivatives as glucagon receptor antagonist | 詹森药业有限公司 | 2019-07-30 | — | — | CN | disclosed |