Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4285209 | 0.78 | MAPT (0.52) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL1716641 | 0.78 | MAPT (0.52) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL30425093 | 0.75 | CYP1A2 (0.46) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL1253014 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL27135550 | 0.73 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL29170463 | 0.72 | CYP1A2 (0.56) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL27028793 | 0.71 | DHPS (0.49) | KDM4ETP53CYP1A2KMT2AMEN1 | |
| SCHEMBL26334263 | 0.70 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL23610830 | 0.69 | BCL6 (0.54) | KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL23610831 | 0.69 | BCL6 (0.54) | KDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072883-A | The relevant peptide of therapeutic MOTS-C | 科巴公司 | 2019-07-30 | — | — | CN | disclosed |