SCHEMBL1716641

SCHEMBL1716641

C[C@H](Nc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.52
KDM4E B2RXH2 2/20 0.52
APAF1 O14727 1/20 0.52
POLB P06746 1/20 0.52
RECQL P46063 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
STING1 Q86WV6 6/20 0.52
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
LMNA P02545 1/20 0.49
MPO P05164 1/20 0.49
TSHR P16473 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49
HIF1A Q16665 1/20 0.49
ALDH1A1 P00352 1/20 0.48
PKM P14618 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NR4A2 P43354 1/20 0.46
CREBBP Q92793 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4285209 1.00 MAPT (0.52) MAPTKDM4EAPAF1POLBRECQL
Tryptophan SCHEMBL1716928 0.86 KDM4E (0.74) MAPTKDM4EAPAF1POLBRECQL
SCHEMBL8407071 0.81 ECE1 (0.55) MAPTKDM4EAPAF1POLBRECQL
SCHEMBL27028793 0.80 DHPS (0.49) MAPTKDM4EKMT2AMEN1LMNA
SCHEMBL25571556 0.80 GPR84 (0.50) MAPTKDM4EL3MBTL1STING1KMT2A
SCHEMBL18642525 0.80 HTR6 (0.39)
SCHEMBL461014 0.80 CYP2A6 (0.43) STING1NR4A2
SCHEMBL22582341 0.79 STING1 (0.45) MAPTKDM4EAPAF1POLBRECQL
SCHEMBL27765284 0.79 PBRM1 (0.48) MAPTKDM4EAPAF1POLBRECQL
SCHEMBL28309358 0.78 KDM4E (0.52) KDM4EKMT2AMEN1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114134186-B Method for synthesizing 5-hydroxy beta-indolylalanine by using glucose as substrate biological method 河北维达康生物科技有限公司 2025-04-22 CN claimed
CN-119607276-A Continuous carbon fiber/PAEK composite material bone fracture plate capable of medical imaging and preparation method thereof 江苏君华特种高分子材料股份有限公司 2025-03-14 CN claimed
CN-114672525-B Biosynthesis method and application of N-acetyl-5-methoxy tryptamine 河北维达康生物科技有限公司 2024-08-09 CN claimed
CN-118142365-A Preparation method of biomacromolecule bridging alginate solvent-resistant gel film 天津工业大学 2024-06-07 CN claimed
CN-114875087-B Method for synthesizing 5-hydroxy beta-indolylalanine by taking beta-indolylalanine as substrate and application thereof 河北维达康生物科技有限公司 2023-08-04 CN claimed
CN-116497411-A Cyanide-free alkaline silver plating electroplating solution and preparation and application thereof 上海电力大学 2023-07-28 CN claimed
CN-114875087-A Method for synthesizing 5-hydroxy beta-indolyl alanine by using beta-indolyl alanine as substrate and application thereof 河北维达康生物科技有限公司 2022-08-09 CN claimed
CN-114672525-A Biosynthesis method and application of N-acetyl-5-methoxytryptamine 河北维达康生物科技有限公司 2022-06-28 CN claimed
CN-114134186-A Method for synthesizing 5-hydroxy beta-indolyl alanine by using glucose as substrate through biological method 河北维达康生物科技有限公司 2022-03-04 CN claimed
EP-2292837-B1 Triazinylaminostilbene disulphonic acid mixtures CLARIANT INT LTD (CH) 2014-06-04 EP claimed
EP-1123929-A1 Fluorescent whitening agents Ciba SC Holding AG (CH) 2001-08-16 EP claimed
WO-2001019804-A1 TRIAZINYLAMINOSTILBENE DERIVATIVE AS FLUORESCENT WHITENING AGENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-03-22 WO claimed
US-6143889-A Asymmetric stilbene compounds CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-11-07 US claimed
US-6143888-A TREATING THE SUBSTRATE WITH A TRIAZINE BASED ULTRAVIOLET ABSORPTION COMPOUND TO INHIBIT THE EFFECT OF AN ANIONIC FLUORECENT WHITENING AGENT CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-11-07 US claimed
WO-2000055688-A1 PROCESS FOR REMOVING STAIN IN A PHOTOGRAPHIC MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-21 WO claimed
EP-0971905-A1 FLUORESCENT WHITENING AGENTS Ciba SC Holding AG (CH) 2000-01-19 EP claimed
EP-0922699-A1 Asymmetric stilbene compounds useful as sun protection agents Ciba SC Holding AG (CH) 1999-06-16 EP claimed
EP-0912530-A2 USE OF TRIAZINE-BASED UVAs FOR USE AS QUENCHERS IN PAPER-MAKING PROCESSES Ciba SC Holding AG (CH) 1999-05-06 EP claimed
WO-1998042685-A1 FLUORESCENT WHITENING AGENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-10-01 WO claimed
WO-1997046541-A2 USE OF TRIAZINE-BASED UVAs FOR USE AS QUENCHERS IN PAPER-MAKING PROCESSES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-12-11 WO claimed