Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | DDX3X | O00571 | 5/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1886330 | 0.73 | MIF (0.71) | MIFDRD2DRD3CYP19A1GABRA2 | |
| SCHEMBL16271203 | 0.73 | MIF (0.71) | MIFDRD2DRD3CYP19A1GABRA2 | |
| Bromide SCHEMBL1880796 | 0.72 | MIF (0.69) | MIFDRD2DRD3CYP19A1GABRA2 | |
| Bromide SCHEMBL1883955 | 0.72 | MIF (0.69) | MIFDRD2DRD3CYP19A1GABRA2 | |
| Bromide SCHEMBL1890839 | 0.72 | MIF (0.69) | MIFDRD2DRD3CYP19A1GABRA2 | |
| Bromide SCHEMBL1880908 | 0.72 | MIF (0.69) | MIFDRD2DRD3CYP19A1GABRA2 | |
| SCHEMBL17978544 | 0.70 | MIF (0.67) | MIFGABRA2GABRB2DDX3XNOTUM | |
| SCHEMBL21974268 | 0.70 | RXRA (0.59) | MIFDDX3X | |
| SCHEMBL17978571 | 0.70 | GABRA2 (0.46) | MIFGABRA2GABRB2DDX3XP2RX7 | |
| SCHEMBL27867442 | 0.69 | DDX3X (0.42) | MIFDRD2DRD3DDX3XP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105355-B | Preparation method of 1,2, 3-triazole- [1,5-a ] quinoline compound | 烟台大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-110105355-A | A kind of preparation method of 1,2,3- triazole-[1,5-a] and quinolines | 烟台大学 | 2019-08-09 | — | — | CN | disclosed |