Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 10/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27867431 | 0.87 | NOTUM (0.40) | DDX3XMIFLDHA | |
| SCHEMBL27867421 | 0.80 | MIF (0.47) | DDX3XMIFLDHA | |
| SCHEMBL27883864 | 0.77 | LDHA (0.51) | MIFLDHA | |
| SCHEMBL27867412 | 0.72 | LDHA (0.57) | LDHA | |
| SCHEMBL14118352 | 0.72 | LDHA (0.63) | DDX3XP2RX7MIFLDHA | |
| SCHEMBL27867459 | 0.70 | AADAT (0.51) | — | |
| SCHEMBL27883825 | 0.70 | AADAT (0.51) | — | |
| SCHEMBL28309985 | 0.69 | MIF (0.49) | DDX3XP2RX7MIFDRD2DRD3 | |
| SCHEMBL29828549 | 0.67 | MAOA (0.66) | DDX3XP2RX7MIFLDHA | |
| SCHEMBL27883834 | 0.67 | AADAT (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639497-A | Compounds inhibitors of enzyme lactate dehydrogenase (LDH) and pharmaceutical compositions containing these compounds | UNIV PISA | 2012-08-15 | — | — | CN | disclosed |