Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28309485 | 0.81 | CES2 (0.47) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL11396201 | 0.79 | KMT2A (0.47) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL13622409 | 0.78 | LMNA (0.56) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL28310210 | 0.76 | NR1H4 (0.58) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL10694146 | 0.75 | KMT2A (0.54) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL28310196 | 0.74 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9279519 | 0.73 | LMNA (0.51) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL11044715 | 0.73 | KMT2A (0.51) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL28310195 | 0.73 | MAPT (0.40) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL25863485 | 0.73 | LMNA (0.55) | MAPTLMNAKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099898-A | compound and use thereof | 优曼尼蒂治疗公司 | 2019-08-06 | — | — | CN | disclosed |